本論文利用問卷及風險評估模式，針對台灣西南沿海四鄉鎮（嘉義縣布袋、義竹及台南縣北門、學甲）進行調查，探討因食用地下水養殖虱目魚而暴露於砷、鋅、銅污染之危害風險。結果顯示，當地養殖池水之砷（63.9 ± 2.51 mg L-1）、銅（77.1 ± 3.69 mg L-1）濃度皆超過台灣二級水產用水標準（砷：50 mg L-1、銅：30 mg L-1）; 鋅濃度（10.9 ± 4.72 mg L-1）則低於標準值（500 mg L-1）。虱目魚體對砷、鋅、銅之生物濃縮因子（BCF）值分別為 12.51 ± 4.95、4479.68 ± 1399.66、30.50 ± 12.76，顯示虱目魚對於周圍水體中的砷、鋅、銅污染質具有累積能力，其中對鋅的吸收、累積能力與耐受性均高於砷、銅。食用地下水養殖虱目魚之標的致癌風險（TR）為 1.05×10-3 ± 9.91×10-4，大於可接受風險標準值 1×10-6約 1000 倍。砷、鋅、銅之非致癌風險標的危害商數（THQ）中，只有砷超過標準值 1。砷、鋅、銅的危害指數（HI）為5.91 ± 5.38，高於標準值5倍以上，其危害性主要源自於砷的THQ值 5.45 ± 5.14。根據理論值求出之虱目魚安全攝取量為 0.32 ± 0.17 g d-1，但當地居民之食用量卻高達 179.32 ± 233.51 g d-1，表示居民若以此攝取量食用當地以地下水養殖之虱目魚，會有高度的致癌和非致癌風險。養殖虱目魚體砷之風險基準濃度（RBCf）為 7.19×10-4 ± 2.62×10-4 mg g-1，但實際採得之虱目魚砷含量卻高過此標準。養殖池水之風險基準砷濃度（RBCw）為 0.08 ± 0.03 mg L-1，而養殖池水之實際砷濃度 63.9 ± 2.51 mg L-1明顯過高。因此若以此池水養殖虱目魚，而後又供居民食用，會使民眾暴露於致癌和非致癌性疾病的風險中。 The risk associated with intake of arsenic（As）, zinc（Zn）and copper（Cu）of cultured milkfish（Chanos chanos）using groundwater from southwest coast in Taiwan were studied, based on the questionnaire and the risk assessment models. The resulting values of As（63.9 ± 2.51 mg L-1）and Cu（77.1 ± 3.69 mg L-1）in pond water show that the concentrations of these two pollutants are higher than the standards in Taiwan（As: 50 mg L-1 and Cu: 30 mg L-1, respectively）, while the Zn concentration（10.9 ± 4.72 mg L-1）is lower than the standard（500 mg L-1）. The bioconcentration factor（BCF）values of As, Zn and Cu in milkfish（12.51 ± 4.95, 4479.68 ± 1399.66 and 30.50 ± 12.76, respectively）show that the milkfish can accumulate these pollutants from the ambient water. The target cancer risk（TR）of consuming milkfish is 1.05×10-3 ± 9.91×10-4, which is higher than the acceptable risk 1×10-6. Among the three pollutants, only the value of the target hazard quotient（THQ）of As exceeds the safe value 1 for non-carcinogenic risk. The hazard index（HI）5.91 ± 5.38 is 5 times higher than the standard, mainly contributed by the THQ value 5.45 ± 5.14 of As. The acceptable consumption of the milkfish is 0.32 ± 0.17 g d-1, which is lower than the actual milkfish consumption 179.32 ± 233.51 g d-1. Therefore, the consumption of cultured milkfish using groundwater may cause carcinogenic and non-carcinogenic risks. The risk-based concentration（RBCf）of As in milkfish is 7.19×10-4 ± 2.62×10-4 mg g-1, which is lower than that in milkfish we measured in pond. Arsenic concentrations（63.9 ± 2.51 mg L-1）in pond water are higher than the risk-based concentration（RBCw）for As（0.08 ± 0.03 mg g-1）. Ingestion of these contaminated milkfish could result in exposure of As, Zn and Cu in inhabitants and lead to adverse health effects caused by As.
