跨領域研究的具體研究方法運用一直是跨領域議題極需釐清的命題。本文著眼於此,嘗試以「藥品廣告規範」的議題為例,從橫跨傳播、健康(醫藥)與法規範等三大領域的命題出發,探討究竟應如何從方法論的視域,具體落實到研究方法的實踐,促使跨領域議題的研究更具可執行性。本文以所主張的「健康素養」概念作為「藥品廣告規範」跨領域議題的解決之道,從借重傳播學研究三大學派與研究三大典範的對話,提出「健康素養」的本體論、認識論與方法論的見解,進而點出跨領域研究選用研究方法與工具之必須克服之處,期待為未來跨領域研究的研究方法問題有所助益。 The concrete research method for interdisciplinary study is always a big problem to interdisciplinary research. Among it, how to use methods on the interdisciplinary issue is perhaps one of the most important topics. For the above-mentioned reason, this article tries to take the regulation of pharmaceutical advertising for instance, crossing communication, health (medicine) and regulation to explore know-how from concept (methodology) to practice (methods) for interdisciplinary study. This article advocates “health literacy” as the best way to solve the problem of regulation of pharmaceutical advertising. With drawing on three paradigms of communication studies, this article structures the ontology, epistemology and methodology of health literacy to select correct methods for so-called communication interdisciplinary research. Through the process of investigating health literacy, this article indicates how to overcome the problem of interdisciplinary research methods to make operationalization more substantial for interdisciplinary study.